Phosphoinositide
3-Kinase enzyme
It is a signal transduction
system that connects oncogenes and multiple receptor classes to many cellular
functions such as cell survival, proliferation and differentiation. The key
enzyme family in this pathway is PI3Ks (Phosphoinositide 3-Kinases) which
transducer signals from various growth factors and cytokines into intracellular
messages by generating phospholipids. These phospholipids activate the serine-
threonine...
